Searchable abstracts of presentations at key conferences in obesity

ob0002cd1.4 | Case Discussions: Complex Clinical Cases 1 | OU2020

Liraglutide downregulates the expression of miRNA-424 in patients with obesity

Dimitriadis Georgios K , Dimitri Federica , Bate Danielle , Leca Bianca , Davasgaium Allan , Tripathi Gyanendra , Miras Alexander D , Rubino Francesco , Christian Mark , Randeva Harpal S

Aims: Liraglutide 3 mg once daily is an approved, prescription injectable Glucagon Like Peptide-1 receptor agonist that, when used with a low-calorie diet and increased physical activity, can reduce excess weight in patients with obesity. MiRNAs are small non-coding single stranded RNAs that regulate gene expression post-transcriptionally by inhibiting their mRNA target translation into proteins. MiRNAs can be secreted in the blood stream and affect the molecular pathways of d...